Home Topics Drug Discovery Page 3

Drug Discovery

Featured posts

Drug Discovery

Metabolic Proteins “Deorphanized” with Gene-Metabolite Association Prediction Tool

Scientists Working in The Laboratory

Drug Discovery

Weight-Loss Drugs Could Exploit Fat Cells’ White-to-Beige Mechanism

neuropsychiatric stress

Drug Discovery

Alzheimer’s Clue: Serotonin C Receptor Has Role in Memory Loss

Lung Cancer

Drug Discovery

Nano-Immunotherapy Delivers Checkpoint Inhibition And Anticancer Drug to Lung Tumors in Mice

Concept of scientist exploring human brain

Drug Discovery

Risk of Diabetes Caused by Antipsychotics Decreased by Pancreas Specific Dopamine Agonist

Prostate Cancer

Drug Discovery

IBS Drug Restores Chemotherapy Effectiveness against Resistant Prostate Cancer

Scientists Discussing and Using Computer Software

Drug Discovery

“SNAF” Computational Tool Identifies Splicing Neoantigen Targets for Immunotherapy

This illustration shows SA (golden spheres) and various antigens and antibodies. Dominant antigens (purple) cause SA to produce non-protective antibodies (red with purple tips). These nonprotective antibodies outcompete antibodies derived from vaccination (green with purple tips). Vaccines targeting subdominant antigens (blue) could help yield more protective antibodies (green with blue tips), making the vaccine more effective.

Drug Discovery

Staph Germs Trick the Immune System to Defeat Vaccines

Graphical abstract of cyclic oral peptides.

Drug Discovery

One-Pot Method for Generating Orally Available Cyclic Peptide Drug Candidates

Closeup of vaccine bottle with syringe and needle for immunization on vintage medical background, medicine and drug concept

Drug Discovery

Nanoparticle Enables Muscle-Focused Delivery of mRNA Vaccines and Therapeutics

woman with her hand on wheel of wheelchair

Drug Discovery

Neuroprotective MS Drug Candidate Rescues Myelin and Motor Function in Mouse...

Lung

Drug Discovery

Allergy Drug Added to Immunotherapy Benefits Lung Cancer Therapy in Small...

Rheumatoid arthritis hands

Drug Discovery

Drug Candidate’s ‘Inside Job’ Obstructs Pain Channel, Avoids Side Effects

iPad In Lab

Drug Discovery

Understanding the Superpower of T-Cell Subtype

The mechanism for a critical but highly toxic antifungal is revealed in high resolution. Self-assembled Amphotericin B sponges rapidly extract sterols from cells. This atomic level understanding yielded a breakthrough kidney-sparing antifungal agent.

Drug Discovery

Researchers Tweak Antifungal Drug to Turn “Ampho-terrible” into “Ampho-terrific”

1 234...21 Page 3 of 21